In a chart like the one below, limitations on the max aircraft weight (upper horizontal line), forward-most CG (left vertical line), and aft-most CG (right vertical line) are fairly easy to understand. However, other limitations can be present as well, such as the diagonal line that cuts off what would be the top-left corner below, so as to disallow some forward CG's at heavier weights that would be okay when lighter.
At a conceptual level, what drives limitations like this diagonal line? What adverse state does adhering to this limit protect against?