https://en.wikipedia.org/wiki/Bomber_B
With engines in the 2,000 to 2,500 hp range, twin-engined aircraft would have considerably more surplus power, allowing for much greater payloads. In theory, the more powerful engine would take no longer to produce than a 1,000 hp design, it would simply be larger. By the late 1930s, engines of this sort of power began to be seriously considered and the British and Germans drew up bomber designs based on them.
https://en.wikipedia.org/wiki/Junkers_Jumo_222
The Jumo 222 was a massive and very costly failure. 289 examples of the Jumo 222's were built in total, none of which saw active service. It also served to seriously hamper Luftwaffe piston-engined designs from 1940 to 1942, while many personnel within the Luftwaffe's government-operated technology development offices (like Oberst Edgar Petersen's chain of several Erprobungsstelle installations) and German military aviation corporate engineering departments waited for the Jumo 222 to finally start working. Meanwhile, all calls for four-engine adaptations in place of twin-engine Jumo 222 powered designs were rejected because it was felt it would place too much strain on the German engine industry. In the end there was nothing to show for it, and late in the war the Luftwaffe was flying barely updated versions of their original pre-war designs.
A bigger engine means bigger or more numerous components. Wouldnt either cause significant increase in time?