For Part 91 flight operations, many pilots will listen to the radio or music. I have often listened to songs on my iPhone music library fed through an aux jack into my headset. And many IFDs and integrated GNSS navigation systems often offer XM weather and XM Radio services through subscription that pilots will use to listen to XM radio, as this SR-22 pilot making a flight out to Camarillo, CA does.
One older option, if the aircraft is equipped with a functioning ADF, is that, since NDBs broadcast in the kilohertz range, pilots can tune an ADF into AM radio stations and put it through to their headsets using the audio panel. The ADF needle will point in the direction of the AM radio transmission tower for that station. AM stations that are tracked this way can be used as a supplemental navaid in VFR operations but are not approved as terrestrial navaids for IFR operations.
Use of visual entertainment such as movies, television programs, video games, etc., is not allowed for a flight crew as they are required to maintain visual scanning outside the aircraft, if able, for situational awareness and collision avoidance.
I can't speak for Part 121 or Part 135 operations but I'd venture a guess that such activity is frowned upon by employers during flight operations. But I'm sure many a 747 or A380 crew over the Pacific at FL410 with another 9.5 hours to go before making Kingsford Smith Intl will listen to the radio or take turns watching outside of the aircraft while the other flight crewmember reads a book or relaxes.
It is important to limit these activities to low workload phases of the flight such as long stretches of cruise in low density airspace and maintain a sterile cockpit during attention intensive phases such as takeoff, departure, approach and landing. I will only listen the the radio in cruise and use is terminated at least 10 minutes before a planned descent begins. A pilot should do a realistic self assessment of his/her flying abilities and refrain from the use of these things if they have difficulties with multitasking or are easily distracted from the airmanship tasks at hand.
Use of entertainment products during emergencies is unacceptable as well.