If an airline pays too much attention to such difference, I would be worried. Very few accidents are caused by improper handling of the controls; the majority are due to poor pilot's decisions and discipline, so I expect airlines to focus on the latter.
Part 61.160 says no:
(b) A person may apply for an airline transport pilot certificate with
an airplane category multiengine class rating or an airline transport
pilot certificate concurrently with an airplane type rating with a
minimum of 1,000 hours of total time as a pilot if the person:
(1) Holds a Bachelor’s degree with an aviation major ...