Edited Wikipedia to show that the last three runways are only available to large aircraft in emergency. The actual rule is no scheduled flights over 9 passengers and no unscheduled commercial flights 31 passengers or more. Reference is the Chart Supplement, but of course that updates frequently so there's no good way to reference it except to say "type MDW into this web form".

This is what the [chart supplement][1] says (7 OCT 2021 to 2 DEC 2021):

>AIRPORT REMARKS: Attended continuously. Birds on and invof arpt. Arpt CLOSED to solo student trng. Rwy 13R–31L, Rwy 13L–31R and Rwy 04L–22R **not avbl for skedd acr opns** with more than 9 psgr seats or unscheduled acr at least 31 psgr seats [...] [emphasis added]


  [1]: https://skyvector.com/airport/MDW/Chicago-Midway-International-Airport