The Centre of Lift (CoL) of the whole aeroplane is a summation of the lift forces of the wing, the fuselage and the horizontal stabiliser. The wing has the largest contribution to the lift of course.
Above figure is from Torenbeek, Synthesis of Subsonic Airplane Design, and shows how to construct the Mean Aerodynamic Chord of a swept wing. The CoL of a subsonic wing is taken at 25% of the MAC in the pre-design phase - this answer provides some more detailed information.
Above pic from this answer shows the relation between CoL, Centre of Gravity and tailplane lift/downforce: it is an equation of moments about the CoG.
The arrow at dC$_{NW}$ is the wing lift, dC$_N$ the composed aeroplane lift, and at dC$_{Nh}$ the tailplane lift. Which can be positive in cruise, however at take-off the stabiliser will need to generate a downforce, shifting the aeroplane lift balance point forwards (the wing lift can still be assumed to be at 25% MAC in this stage of your design).
If CoL of the complete plane is in front of the CoG, the nose of the aeroplane will tilt up.