The localizer for runway 09 is offset by 3°, almost certainly because of terrain. That would be a typical reason for a non-standard installation.
The approach plate for the LOC RWY 09 approach notes the offset (more than 3° and it would be an LDA approach):
The final approach course for the LOC 09 is 093°, whereas for the two RNAV (GPS) approaches it's 096°, which is also the current magnetic heading of the runway. The Chart Supplement has various notes indicating that terrain is an issue (and RWY 09 has a displaced threshold) so everything indicates that the localizer is offset slightly for that reason, presumably to avoid signal interference.
As for practical issues for pilots, correcting for a 3° offset shouldn't be a problem. A bigger consideration seems to be that the MDA on the LOC 09 approach is more than 2000' AGL so if the pilot breaks out late he'll very likely have to circle to land.