The principal reason plane crashes are less survivable, which nobody really seems to fully grasp when talking about airliners, is the sheer amount of energy inherent in a commercial airplane. When you watch a plane coming in for approach, especially a big one like a 747 or A380, it usually seems very docile, with the plane very slowly and gently approaching the runway. The other classic image is the plane cruising at high altitude, perhaps leaving a contrail behind it as it slowly tracks across the sky. We compare these images from our experience to images of cars zooming past us along a busy road (or a racetrack). We then watch racecar drivers walk away from spectacular wrecks, while plane crashes kill everyone aboard, and we wonder why planes can't be made as safe as racecars (or even ordinary passenger cars).
That image of the docile aircraft traversing the friendly skies, however, is a forced perspective caused by a much bigger object much further away from us, and belies the fact that dozens or even hundreds of tons of weight is moving up to three times faster than an Indy car has even been clocked.
Basic projectile physics; $E = \frac{1}{2}mv^2$. The car in your driveway, if typical, has a "curb weight" (empty tank but otherwise ready to drive) of about a ton and a half, and cruises at speeds between 30 and 70 mph. Converting mph to fps (multiply by 5280, divide by 3600), the energy, in foot-pounds, of a 3000lb car at a freeway speed of 60mph is about 23 million foot-pounds, plus the additional kinetic energy of driver, passengers and cargo. In a collision, this energy is transferred wherever it will go; the object being collided with, the frame of the car, its occupants, etc. Even at these speeds, a collision can permanently injure or kill someone inside (and a full-speed collision on the highway is more often fatal than not).
A typical airliner, say the B737-700 which is in common use in the U.S. domestic fleet, has an "operating empty mass" (similar to "curb weight" in cars; everything needed to fly except the fuel and flight crew) of about 40 tons. So right there the potential energy of the airliner is 30-40 times the car. It also takes off and lands at roughly 125-150mph, and cruises at up to Mach 0.78, which at 30,000 ft is about 525mph. So, we're also talking about an order of magnitude difference in velocity, and that increases total energy on the square. Doing the math, an airliner at cruising speed, not counting the energy inherent in its cargo or passengers, will have a total kinetic energy somewhere on the order of 50 billion foot-pounds. Even with all other things being equal, such as the distance allowed for deceleration and the distribution of impact forces to the passengers, a passenger in a plane crash would be subjected to more than ten times the forces they would in a car crash.
Now, all these things can be mitigated in both cases. These numbers more or less compare what a passenger in a car vs a plane would go through if the vehicle plowed head-on into an immovable obstruction at full speed. That doesn't happen often in either case; highways are built in part to minimize the chance a driver will ever face a barrier head-on, and drivers can usually hit the brakes to slow the car and steer to hit in an oblique direction, and even if that won't prevent an impact it lessens the severity of it by the square of the change in relative speed between the car and what it's hitting.
Similarly, a CFIT (Controlled Flight Into Terrain) is pretty much the worst case scenario for a plane crash (the only worse one I can think of being a midair collision which is extremely rare especially for airliners), and there are a lot of systems aboard the aircraft to help a pilot realize he's about to do that. A crash landing, such as a belly landing due to hydraulic failure, is usually more survivable because the pilot is doing everything he can to minimize the force of impact and the plane's total kinetic energy, by both slowing the plane's forward velocity and reducing the glide slope. The plane's remaining kinetic energy can then be spent skidding down the runway or over the field instead of being imparted directly into the aircraft's frame and ultimately its passengers.
However, that's still a lot of energy for the plane to get rid of, and even with the inherent weight of an airliner, the ability to fly is favored by designers over keeping the cabin in one piece in a crash. That means that the inherently higher risk to life and limb of flying must be mitigated by keeping the planes well-maintained, and putting well-trained, experienced, healthy flight crews in them. Neither can be said for the average car and driver plucked off the street; only the most severe medical conditions are grounds for revocation of a driver's license, while most cars are driven thousands of miles past scheduled maintenance intervals. Cars, therefore, must be designed and built to keep the occupants alive in a collision, despite the ability or even the intentions of the driver. A plane's safety features are only useful when the pilot is doing his job properly; an oxygen mask or even an escape hatch is useless in a CFIT.