I know this question is somewhat general and could vary from plane to plane so I will elaborate on the plane in question.
The specific plane I am curious about is the Mooney Mite which has a metal center section but wooden wings and wooden rear half and empennage which at the age most of these planes are is prone to issues. It seems like a great little plane.
My question is can one be built out of aluminum to the same specs (maybe with a bigger engine) and still fly properly or will the weight change (CG change) affect the plane too drastically?
Likewise could a Piper Cub or similar be made of all metal (again with a bit more power up front) and still be an effective plane?
For the record I do not currently have plans to build this plane (although it was available as a kit plane at some point in history. I am aware of the certification issues with making alterations like to an existing plane. I was asking more about if it was possible from an aeronautical standpoint.